Nitrocefin

A chromogenic ß-lactamase substrate that undergoes distinctive color change from yellow (Amax = 390 nm at pH 7.0) to red (Amax = 486 nm at pH 7.0) as the amide bond in the ß- lactam ring is hydrolyzed by ß-lactamase. Nitrocefin is sensitive to hydrolysis by all known lactamases produced by Gram-positive and Gram-negative bacteria. Also useful for the detection of ß-lactamase patterns from bacterial cell extracts by isoelectric focusing. Has been used in competitive inhibition studies in developmental work on ß-lactamase-resistant antibiotics.

Molecular Formula
C20H2005
Description
A chromogenic β-lactamase substrate that undergoes distinctive color change from yellow as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase.
CAS No.
41906-86-9
Specification
Molecular Weight 340.37
FormPowder
AppearanceOrange yellow solid powder
Purity (HPLC)<99%
Assay≥95% (UV)
Grade
Packaging
Storage & Handling
Applications

It is a tool for detecting β-lactamase activity in kits and reagents

Certifications
Shipping Information
H.S. Code
Structure
01
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